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Antigenic Specificity | RAF1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Raf-1 is a MAP kinase kinase kinase (MAP3K) which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated Raf-1 can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2 which in turn phosphorylate to activate the serine/threonine specific protein kinases ERK1 and ERK2. |
Immunogen | Immunogen: A synthesized peptide derived from human Raf1 |
Other Names | [C-RAF, C-Raf, CRAF, EC 2.7.11.1, Protein kinase raf 1, RAF1, Raf proto-oncogene serine/threonine-protein kinase, Raf-1, kinase Raf1] |
Gene, Accession # | [RAF1], Gene ID: 5894, NCBI: NP_002871.1, UniProt: P04049 |
Catalog # | MBS8542315 |
Price | $280 |
Order / More Info | RAF1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |