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Antigenic Specificity | STRAD |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total STRAD protein. Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation.Scanlan M.J., Cancer Immun. 1:4-4(2001). Ota T., Nat. Genet. 36:40-45(2004). Baas A.F., EMBO J. 22:3062-3072(2003). |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human STRAD. |
Other Names | [STE20-related adapter protein; STRAD alpha; Serologically defined breast cancer antigen NY-BR-96; STRAD; LYK5] |
Gene, Accession # | [STRAD], Gene ID: 92335, NCBI: NP_001003786.1, UniProt: Q7RTN6 |
Catalog # | MBS9410040 |
Price | $200, $255 |
Order / More Info | STRAD Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |