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Antigenic Specificity | UHRF1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint. It is regarded as a hub protein for the integration of epigenetic information. This gene is up-regulated in various cancers, and it is therefore considered to be a therapeutic target. Multiple transcript variants encoding different isoforms have been found for this gene. A related pseudo |
Immunogen | Immunogen: Recombinant protein of human UHRF1 |
Other Names | [ICBP90; Np95; RNF106; TDRD22; hNP95; hUHRF1; huNp95] |
Gene, Accession # | [UHRF1], Gene ID: 29128, NCBI: Q96T88.1, UniProt: Q96T88 |
Catalog # | MBS9132482 |
Price | $200, $275, $430 |
Order / More Info | UHRF1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |