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Antigenic Specificity | Unphosphorylated-N-WASP(S484/S485) [WASP (S483/S484)] |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody was cross-adsorbed to phospho-N-WASP (S484/S485) peptide (without carrier) then affinity purified using unphosphorylated N-WASP (S484/S485) peptide (without carrier). The antibody detects a 65 kDa* protein on SDS-PAGE immunoblots of rat brain and SKN-SH cell lysates that are treated with alkaline phosphatase. Only low levels of unphosphorylated WASP or N-WASP are detected in untreated rat brain, Jurkat, and A431 cells. Members of the Wiskott-Aldrich sydrome protein (WASP) family regulate the formation of actin-based cell structures in many cell types. These proteins contain C-terminal actin-binding domains that can stimulate actin polymerization. In addition, these proteins bind the ARP2/3 complex, which can nucleate actin pol |
Immunogen | Immunogen: Unphosphorylated N-WASP (S484/S485) synthetic peptide (coupled to KLH) corresponding to amino acid residues around serine 484 and 485 of human N-WASP. The human WASP sequence has a similar peptide sequence surrounding serine 483 and 484. |
Other Names | n/a |
Gene, Accession # | n/a |
Catalog # | MBS472064 |
Price | $385 |
Order / More Info | Unphosphorylated-N-WASP(S484/S485) [WASP (S483/S484)] Antibody from MYBIOSOURCE INC. |
Product Specific References | • Higgs, H.N. & Pollard, T.D. (2001) Annu Rev Biochem 70:649-676.• Cory, G.O. et al. (2003) Mol Cell. 11(5):1229-39. |