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Antigenic Specificity | ROR2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | n/a |
Format | APC-Cy7 conjugate |
Size | 0.1 mg |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Detects 104.7 kDa. Bands at ~60, 35 kDa are possible degradation products. ROR2 is a receptor tyrosine kinase which may have a role in early cartilage and growth plate development. ROR2 expression is generally highest during embryonic development and will gradually decrease as cells terminally differentiate. Wnt5a has been identified to utilize ROR2 as a co-receptor for non-canonical Wnt signalling. Aberrant expression of ROR2 has been implicated in gastric, osteosarcoma, mestatic melanoma, prostate, renal cell and squamous cell carcinomas. Increased expression of ROR2 was correlated with increased metastasis. In prostate, osteosarcomas and metastatic melanomas, Wnt5a/ROR2 receptor complex formation was implicated as the mechanism for cance |
Immunogen | Immunogen: Synthetic peptide of Human ROR2 (100-200 aa), conjugated to Keyhole Limpet Haemocyanin (KLH). |
Other Names | [Rabbit Human ROR2; NTRKR2; Tyrosine-protein kinase transmembrane receptor ROR2; receptor-related 2; ROR2; Neurotrophic tyrosine kinase; Receptor tyrosine kinase-like orphan receptor 2; Neurotrophic tyrosine kinase; receptor related 2] |
Gene, Accession # | [ROR2], Gene ID: 4920, NCBI: Q01974.2, UniProt: Q01974 |
Catalog # | MBS8005147 |
Price | $510 |
Order / More Info | ROR2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |