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Antigenic Specificity | Phospho-P21CIP1 (T57) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.32 |
Applications | Dot Blot (DB), ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This P21CIP1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T57 of human P21CIP1. This gene encodes a potent cyclin-dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin-CDK2 or -CDK4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli. This protein can interact with proliferating cell nuclear antigen (PCNA), a DNA polymerase accessory factor, and plays a regulatory role in S p |
Immunogen | n/a |
Other Names | [Cyclin-dependent kinase inhibitor 1; CDK-interacting protein 1; Melanoma differentiation-associated protein 6; MDA-6; p21; CDKN1A; CAP20; CDKN1; CIP1; MDA6; PIC1; SDI1; WAF1] |
Gene, Accession # | [CDKN1A], Gene ID: 1026, NCBI: NP_000380.1, UniProt: P38936 |
Catalog # | MBS9206243 |
Price | $165, $370 |
Order / More Info | Phospho-P21CIP1 (T57) Antibody from MYBIOSOURCE INC. |
Product Specific References | Scott, S.A., et al., Leuk. Res. 28(12):1293-1301 (2004). Amini, S., et al., J. Biol. Chem. 279(44):46046-46056 (2004). Chen, T., et al., Cancer Res. 64(20):7412-7419 (2004). Sieburg, M., et al., J. Virol. 78(19):10399-10409 (2004). Giraud, S., et al., Oncogene 23(44):7391-7398 (2004). |