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Antigenic Specificity | Mast Cell Chymase (CMA1) |
Clone | polyclonal |
Host Species | Sheep |
Reactive Species | human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.1 mg |
Concentration | ~0.2mg/ml (after reconstitution) |
Applications | ELISA (EL/EIA), Western Blot (WB), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes human Chymase. Crossreactivity: ~10% with MCPT1 and <1% with rhGranzyme-B, rhGranzyme-H, rmMCPT6 and rmMCPT7. Chymase (also mast cell protease I) is a secreted, 30kD glycoprotein member of the granzyme subfamily, peptidase S1 family of enzymes. It is secreted by mast cells and vascular smooth muscle cells, and converts angiotensin I into angiotensin II. This promotes fibroblast proliferation and secretion of ECM. Mature human chymase is 226aa in length. It contains one peptidase S1 domain (aa22-245). There is one potential alternate splice form. It shows a deletion of the 99 C-terminal amino acids (aa49-247). |
Immunogen | Immunogen: Recombinant protein corresponding to Gly20-Asn247 from human Chymase expressed in NS0 cells. |
Other Names | [-Mast Cell Chymase (CMA1)], [CMA1; CMA1; CYH; MCT1; chymase; MGC119890; MGC119891; CYH; CYM] |
Gene, Accession # | Gene ID: 1215, UniProt: P23946 |
Catalog # | MBS618805 |
Price | $780 |
Order / More Info | Mast Cell Chymase (CMA1) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |