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Antigenic Specificity | ADAM10 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 500 ug/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Proinflammatory cytokine tumor necrosis factoralpha contributes to a variety of inflammatory responses and programmed cell death. Notch receptor and its ligand participate in cell fate decisions during vertebrate development and are associated with several human disorders, including a T-cell lymphoma. TNF-alpha, notch and its ligand delta are all membrane-bond molecules, which are cleaved by proteases to release mature proteins or functional receptor. ADAM10, a metalloprotease-disintegrin in the family of mammalian ADAM, was recently identified to cleave TNF-alpha, notch and its ligand delta. The genes encoding human, mouse, and bovine ADAM10 were recently cloned and designated ADAM10, kuzbanian, and MADM, respectively. ADAM10 mRNA is expre |
Immunogen | Immunogen: ADAM10 antibody was raised in Rabbit using synthetic peptide corresponding to residue surrounding amino acid 735 of human ADAM10 as the immunogen. |
Other Names | [Rabbit ADAM10; ADAM10; ADAM10; MADM; EC 3.4.24.81; ADAM 10; kuz; CD156c; HsT18717; ADAM-10; CDw156; ADAM10; ADAM-10; ADAM 10] |
Gene, Accession # | [ADAM10], Gene ID: 102 |
Catalog # | MBS5311216 |
Price | $475 |
Order / More Info | ADAM10 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |