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Antigenic Specificity | TLR9 |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg, 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Controls lymphocyte response to Helicobacter infection. |
Immunogen | Immunogen: A synthesized peptide derived from human TLR9. Subcellular Localization: Endoplasmic reticulum membrane; Single-pass type I membrane protein. Endosome. Lysosome. Cytoplasmic vesicle, phagosome. Relocalizes from endoplasmic reticulum to endosome and lysosome upon stimulation with agonist. Tissue Specificity: Highly expressed in spleen, lymph node, tonsil and peripheral blood leukocytes, especially in plasmacytoid pre- dendritic cells. Levels are much lower in monocytes and CD11c+ immat |
Other Names | [Toll-like receptor 9; CD289; TLR9; UNQ5798/PRO19605], [TLR9; TLR9; CD289] |
Gene, Accession # | [TLR9], Gene ID: 54106, NCBI: NP_059138.1, UniProt: Q9NR96 |
Catalog # | MBS179181 |
Price | $160, $340, $340 |
Order / More Info | TLR9 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |