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Antigenic Specificity | IL-15 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC-P) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: At least two isoforms of IL-15 are known to exist. IL-15 Antibody: Interleukin 15 (IL-15) is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and IL-2 share many biological activities as both have been found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between IL-15 and IL-2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. In mouse, studies suggest that IL-15 may increase the expression of apoptosis inhibitor Bcl-xL, |
Immunogen | Immunogen: Rabbit polyclonal IL-15 antibody was raised against a 13 amino acid peptide near the center of human IL-15. Buffer: IL-15 Antibody is supplied in PBS containing 0.02% sodium azide. Positive control: MBS153639 Rat Spleen Tissue Lysate |
Other Names | [IL-15; IL-15; Interleukin-15; IL-15; interleukin 15], [IL15; IL15; IL-15; IL-15] |
Gene, Accession # | [IL15], Gene ID: 3600, NCBI: NP_000576, UniProt: P40933 |
Catalog # | MBS153639 |
Price | $375 |
Order / More Info | IL-15 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |