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Antigenic Specificity | Nibrin (Phospho Ser278) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-Nibrin (S278) Polyclonal Antibody detects endogenous levels of Nibrin protein only when phosphorylated at S278. Mutations in NBN are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. |
Immunogen | Immunogen: Synthesized peptide derived from human Nibrin around the phosphorylation site of S278 |
Other Names | [Rabbit Nibrin (phospho Ser278); NBS; NBS1; P95; Nibrin; Cell cycle regulatory protein p95; Nijmegen breakage syndrome protein 1] |
Gene, Accession # | [NBN], Gene ID: 4683, NCBI: NP_002476.2, UniProt: O60934 |
Catalog # | MBS9705970 |
Price | $130, $220, $325 |
Order / More Info | Nibrin (Phospho Ser278) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |