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Antigenic Specificity | PRKAG1 (N-term), 1-30 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This PRKAG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human PRKAG1. The protein encoded by this gene is a regulatory subunitof the AMP-activated protein kinase (AMPK). AMPK is a heterotrimerconsisting of an alpha catalytic subunit, and non-catalytic betaand gamma subunits. AMPK is an important energy-sensing enzyme thatmonitors cellular energy status. In response to cellular metabolicstresses, AMPK is activated, and thus phosphorylates andinactivates acetyl-CoA carboxylase (ACC) and beta-hydroxybeta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved inregulating de novo biosynthesis of fatty acid and chol |
Immunogen | n/a |
Other Names | [5'-AMP-activated protein kinase subunit gamma-1; AMPK gamma1; AMPK subunit gamma-1; AMPKg; PRKAG1] |
Gene, Accession # | [PRKAG1], Gene ID: 5571, NCBI: NP_001193638.1, UniProt: P54619 |
Catalog # | MBS9213246 |
Price | $165, $370 |
Order / More Info | PRKAG1 (N-term), 1-30 Antibody from MYBIOSOURCE INC. |
Product Specific References | Jablonski, K.A., et al. Diabetes 59(10):2672-2681(2010) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Jassim, G., et al. Pharmacopsychiatry (2010) In press : Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010) McGeachie, M., et al. Circulation 120(24):2448-2454(2009) |