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Antigenic Specificity | Aurora B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Entrez Summary: May be directly involved in regulating the cleavage of polar spindle microtubules and is a key regulator for the onset of cytokinesis during mitosis. Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Phosphorylates 'Ser-10' and 'Ser-28' of histone H3 during mitosis. Required for kinetochore localization of BUB1 and SGOL1. Interacts with INCENP. |
Immunogen | Immunogen: A synthesized peptide derived from human Aurora B. Sensitivity: Aurora B Antibody detects endogenous levels of total Aurora B |
Other Names | [AIK2; AIM-1; AIM1; ARK2; AURKB; Aurora- and Ipl1-like midbody-associated protein 1; Aurora-B; Aurora-related kinase 2; Aurora/IPL1-related kinase 2; EC 2.7.11.1; STK-1; STK12; Serine/threonine protein kinase 12], [AURKB; AURKB; AIK2; AIM1; ARK2; AurB; IPL1; STK5; AIM-1; STK12; PPP1R48; aurkb-sv1; aurkb-sv2; AIK2; AIM1; AIRK2; ARK2; STK1; STK12; STK5; AIM-1; ARK-2; Aurora-related kinase 2] |
Gene, Accession # | [Aurora B], Gene ID: 9212, NCBI: NP_001243763.1, UniProt: Q96GD4 |
Catalog # | MBS477156 |
Price | $335 |
Order / More Info | Aurora B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |