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Antigenic Specificity | C11B2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of C11B2 protein. CYP11B2 encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane. The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity. Mutations in this gene cause corticosterone methyl oxidase deficiency. |
Immunogen | Immunogen: Synthesized peptide derived from part region of human C11B2 protein at amino acid sequence of 280-360 |
Other Names | [Rabbit C11B2; Cytochrome P450 11B2, mitochondrial; Aldosterone synthase; ALDOS; Aldosterone-synthesizing enzyme; CYPXIB2; Cytochrome P-450Aldo; Cytochrome P-450C18; Steroid 18-hydroxylase] |
Gene, Accession # | [C11B2], Gene ID: 1585, NCBI: NP_000489.3, UniProt: P19099 |
Catalog # | MBS9708523 |
Price | $130, $220, $325 |
Order / More Info | C11B2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |