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Antigenic Specificity | Argonaute 2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Required for RNA-mediated gene silencing (RNAi) by the RNA-induced silencing complex (RISC). Can also upregulate the translation of specific mRNAs under certain growth conditions. Binds to the AU element of the 3'-UTR of the TNF (TNF-alpha) mRNA and upregulates translation under conditions of serum starvation. Also required for transcriptional gene silencing (TGS), in which short RNAs known as antigene RNAs or agRNAs direct the transcriptional repression of complementary promoter regions. |
Immunogen | Immunogen: A synthesized peptide derived from human Argonaute 2 |
Other Names | [Argonaute 2; dAgo2; eIF2C 2; hAgo2; PPD] |
Gene, Accession # | [AGO2], Gene ID: 27161, NCBI: Q9UKV8.3, UniProt: Q9UKV8 |
Catalog # | MBS8543101 |
Price | $280 |
Order / More Info | Argonaute 2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |