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Antigenic Specificity | Human PAK1 (pThr84) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti Human PAK1 (pThr84) antibody recognizes PAK1 when phosphorylated at threonine 84. Serine/threonine-protein kinase PAK1 is an enzyme that in humans is encoded by the PAK1 gene. PAK proteins are critical effectors that link the Rho GTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins are a family of serine/threonine p21-activated kinases and include PAK1-6. These proteins serve as targets for small GTP binding proteins such as OSR1. OSR1, oxidative stress response 1, is activated by osmotic stresses including sorbitol or NaCl. It has been predicted that OSR1 phosphorylates PAK1 in the regulatory domain at Thr84 and inhibits activation of the JNK and MAPK signaling pathway. PAK proteins also serve as targets f |
Immunogen | n/a |
Other Names | [Serine/threonine-protein kinase PAK 1; Serine/threonine-protein kinase PAK 1; serine/threonine-protein kinase PAK 1; p21 protein (Cdc42/Rac)-activated kinase 1; Alpha-PAK; p21-activated kinase 1; PAK-1; p65-PAK], [PAK1; PAK1; PAKalpha; PAK-1] |
Gene, Accession # | [PAK1], Gene ID: 5058, NCBI: Q13153.2, UniProt: Q13153 |
Catalog # | MBS224936 |
Price | $470 |
Order / More Info | Human PAK1 (pThr84) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |