Edit |   |
---|---|
Antigenic Specificity | Fe65, |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Amyloid precursor protein (APP) plays a central role in the pathogenesis of Alzheimer's disease (AD). FE65 is a signaling adaptor of APP protein. The FE65/APP complex was shown to translocate into the cell nucleus and regulate gene expression. Genetic studies in mice validated FE65-APP interaction and molecular studies provided evidence on the role of the complex in abnormal signaling detected in brains of Alzheimer Disease patients. |
Immunogen | Immunogen: Peptide corresponding to residues surrounding Thr668 of human APP695 |
Other Names | [FE65; Amyloid beta A4 precursor protein-binding family B member 1; amyloid beta A4 precursor protein-binding family B member 1; amyloid beta precursor protein binding family B member 1; Protein Fe65], [Apbb1; Apbb1; FE65; Fe65] |
Gene, Accession # | [FE65], Gene ID: 29722, NCBI: AAK20835.1 |
Catalog # | MBS555150 |
Price | $405 |
Order / More Info | Fe65, Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |