JNK2 (MAPK9) (C-term), 349-379 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | JNK2 (MAPK9) (C-term), 349-379 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This JNK2 (MAPK9) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 349-379 amino acids from the C-terminal region of human JNK2 (MAPK9). JNK2 responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as c-Jun and ATF2 and thus regulates AP-1 transcriptional activity. In T-cells, JNK1 and JNK2 are required for polarized differentiation of T-helper cells into Th1 cells. JNK2 isoforms display different binding patterns: alpha-1 and alpha-2 preferentially bind to c-Jun, whereas beta-1 and beta-2 bind to ATF2. However, there is no correlation between binding and phosphorylation, which is achieved |
| Immunogen | n/a |
| Other Names | [Mitogen-activated protein kinase 9; MAP kinase 9; MAPK 9; JNK-55; Stress-activated protein kinase 1a; SAPK1a; Stress-activated protein kinase JNK2; c-Jun N-terminal kinase 2; MAPK9; JNK2; PRKM9; SAPK1A] |
| Gene, Accession # | [MAPK9], Gene ID: 5601, NCBI: NP_001128516.1, UniProt: P45984 |
| Catalog # | MBS9212752 |
| Price | $165, $370 |
| Order / More Info | JNK2 (MAPK9) (C-term), 349-379 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Gupta, S., et al., EMBO J. 15(11):2760-2770 (1996). Sluss, H.K., et al., Mol. Cell. Biol. 14(12):8376-8384 (1994). Kallunki, T., et al., Genes Dev. 8(24):2996-3007 (1994). Fleming, Y., et al., Biochem. J. 352 Pt 1, 145-154 (2000). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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