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Antigenic Specificity | Human Semaphorin 4D |
Clone | [5D40] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The Semaphorins make up the largest family of axon guidance cues yet described. Semaphorins are divided into 8 classes (classes 3-7 found in vertebrates). Class 3 Semaphorins are secreted, classes 4 through 6 are transmembrane proteins, and class 7 are membrane associated via glycosylphosphatidylinositol (GPI) linkage. They are characterized structurally by a conserved ~400 amino acid sema domain. They are classically described as collapsing factors and mediators of axon repulsion, although they may also act as context-dependent chemoattractants. Semaphorins have been shown to have roles in cardiovascular development and in the regulation of immune cell antigen presentation. Receptors or receptor complexes that mediate semaphorin signaling |
Immunogen | n/a |
Other Names | [Semaphorin-4D; Semaphorin-4D; semaphorin-4D; semaphorin 4D; A8; BB18; GR3; CD_antigen: CD100], [SEMA4D; SEMA4D; CD100; SEMAJ; coll-4; C9orf164; M-sema-G; C9orf164; CD100; SEMAJ] |
Gene, Accession # | Gene ID: 10507, NCBI: Q92854.1, UniProt: Q92854 |
Catalog # | MBS692371 |
Price | $490 |
Order / More Info | Human Semaphorin 4D Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |