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Antigenic Specificity | GA45B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of GA45B protein. GADD45B (Growth Arrest And DNA Damage Inducible Beta) is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. GADD45B in this group respond to environmental stresses by mediating activation of the p38/JNK pathway. This activation is mediated via their proteins binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. The function of these genes or their protein products is involved in the regulation of growth and apoptosis. These genes are regulated by different mechanisms, but they are often coordinately expressed and can function cooperatively |
Immunogen | Immunogen: Synthesized peptide derived from part region of human GA45B protein at amino acid sequence of 90-170 |
Other Names | [Rabbit GA45B; Growth arrest and DNA damage-inducible protein GADD45 beta; Myeloid differentiation primary response protein MyD118; Negative growth regulatory protein MyD118] |
Gene, Accession # | [GA45B], Gene ID: 4616, NCBI: NP_056490.2, UniProt: O75293 |
Catalog # | MBS9709180 |
Price | $130, $220, $325 |
Order / More Info | GA45B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |