Edit |   |
Antigenic Specificity | Caveolin-1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunohistochemistry (IHC) Formalin, Immunocytochemistry ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Caveolin-1(CAV1) detection. Tested with WB, IHC-P, IHC-F, ICC in Human, Mouse, Rat. Background: CAV1, Caveolin-1, is a protein that in humans is encoded by the CAV1 gene. The CAV1 gene is mapped to 7q31.2. The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 MAP kinase cascade. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Caveolin-1 (164-178aa GKIFSNVRINLQKEI), different from the related rat and mouse sequences by three amino acids. |
Other Names | [Caveolin-1; caveolin 1, caveolae protein, 22kDa; CAV 1; CAV; CAV1; CAV1_HUMAN; caveolae protein, 22 kD; caveolin 1 alpha isoform; caveolin 1 beta isoform; Caveolin 1 caveolae protein 22kDa; Caveolin-1; Caveolin1; cell growth-inhibiting protein 32; MSTP085; OTTHUMP00000025031; VIP 21; VIP21], [CAV1; CAV1; CGL3; PPH3; BSCL3; LCCNS; VIP21; MSTP085; CAV] |
Gene, Accession # | [CAV1], Gene ID: 857, NCBI: Q03135.4, UniProt: Q03135 |
Catalog # | MBS175723 |
Price | $315 |
Order / More Info | Caveolin-1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |