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Antigenic Specificity | CK-1alpha (Phospho-Tyr294) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of CK-1a only when phosphorylated at tyrosine 294. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May play a role in segregating chromosomes during mitosis.Tapia C., FEBS Lett. 349:307-312(1994).Fish K.J., J. Biol. Chem. 270:14875-14883(1995).Halleck A., Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases. |
Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of tyrosine 294 (Y-D-Y(p)-T-F) derived from Human CK-1a. |
Other Names | [CK-1a (Phospho-Tyr294); KC1A; CKI-alpha; CSNK1A1; alpha isoform; Casein kinase I] |
Gene, Accession # | [CK-1alpha], Gene ID: 1452, NCBI: NP_001020276.1, UniProt: P48729 |
Catalog # | MBS9413909 |
Price | $200, $255 |
Order / More Info | CK-1alpha (Phospho-Tyr294) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |