LRRK2 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | LRRK2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | epitope affinity purified |
| Size | 0.1 mg |
| Concentration | Size: 100 ug/200 ul |
| Applications | ELISA, Western Blot, Immunohistochemistry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody recognizes ~285 kDa of human LRRK2 protein. The other species are not tested. The leucine-rich repeat kinase family (LRKK) proteins are consists of an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40. Various genes and loci (alpha-synuclein/PARK1 and 4, parkin/PARK2, UCH-L1/PARK5, PINK1/PARK6, DJ-1/PARK7, LRRK2/PARK8, synphilin-1 and NR4A2) are associated to Parkinson's Disease (PD). LRRK2 may play an important role as a therapeutic target for treatment of PD (5). |
| Immunogen | Antigen Preparation: A synthetic peptide corresponding to C-terminus of human LRRK2. |
| Other Names | [Rabbit LRRK2; Leucine-Rich Repeat Kinase 2; PARK8; ROCO2; Dardarin; BC300-267; Parkinson disease (autosomal dominant) 8], [LRRK2; LRRK2; PARK8; RIPK7; ROCO2; AURA17; DARDARIN] |
| Gene, Accession # | [LRRK2], Gene ID: 120892, NCBI: NP_940980.3, UniProt: Q17RV3 |
| Catalog # | MBS462071 |
| Price | $285 |
| Order / More Info | LRRK2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Melrose, HL, et al. A comparative analysis of leucine-rich repeat kinase 2 (LRRK2) expression in mouse brain and Lewy Body disease. Neurosci. 147: 1047-1058 (2007) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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