Cdc6 (N-term), 32-61 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCdc6 (N-term), 32-61
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.43
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionThis Cdc6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 32-61 amino acids from the N-terminal region of human Cdc6. Human Cdc6 is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins.
Immunogenn/a
Other Names[Cell division control protein 6 homolog; CDC6-related protein; Cdc18-related protein; HsCdc18; p62(cdc6); HsCDC6; CDC6; CDC18L]
Gene, Accession #[CDC6], Gene ID: 990, NCBI: NP_001245.1, UniProt: Q99741
Catalog #MBS9213446
Price$165, $370
Order / More InfoCdc6 (N-term), 32-61 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesAlexandrow, M.G., et al., Mol. Cell. Biol. 24(4):1614-1627 (2004). Yim, H., et al., Mol. Biol. Cell 14(10):4250-4259 (2003). Clay-Farrace, L., et al., EMBO J. 22(3):704-712 (2003). Pelizon, C., et al., EMBO Rep. 3(8):780-784 (2002). Bermejo, R., et al., Mol. Biol. Cell 13(11):3989-4000 (2002).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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