Edit |   |
---|---|
Antigenic Specificity | PMAIP1 - middle region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1 (By similarity). Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1. |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Mouse PMAIP1 |
Other Names | [phorbol-12-myristate-13-acetate-induced protein 1; Phorbol-12-myristate-13-acetate-induced protein 1; phorbol-12-myristate-13-acetate-induced protein 1; phorbol-12-myristate-13-acetate-induced protein 1; Protein Noxa] |
Gene, Accession # | [PMAIP1], Gene ID: 58801, NCBI: NP_067426.1, UniProt: Q9JM54 |
Catalog # | MBS3223682 |
Price | $335 |
Order / More Info | PMAIP1 - middle region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |