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Antigenic Specificity | Human JARID1B |
Clone | [JARIA3D4] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.1 mg |
Concentration | 100 ug/ml (1.0 ml) |
Applications | Dot Blot (DB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9' or H3 'Lys-27'. Demethylates trimethylated, dimethylated and monomethylated H3 'Lys-4'. Acts as a transcriptional corepressor for FOXG1B and PAX9. Favors the proliferation of breast cancer cells by repressing tumor suppressor genes such as BRCA1 and HOXA5. In contrast, may act as a tumor suppressor for melanoma. [UniProtKB Function] |
Immunogen | n/a |
Other Names | [Homo sapiens Jumonji, AT rich interactive domain 1B (RBP2-like) (JARID1B); PUT1; PLU-1; FLJ10538; FLJ12459;FLJ12491; FLJ16281; FLJ23670; RBBP2H1A], [KDM5B; KDM5B; CT31; PLU1; PUT1; PLU-1; JARID1B; PPP1R98; RBBP2H1A] |
Gene, Accession # | [JARID1B], Gene ID: 10765, NCBI: NP_006609.3 |
Catalog # | MBS120120 |
Price | $395 |
Order / More Info | Human JARID1B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |