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Antigenic Specificity | Human IRAK1 (C-TERMINAL) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | IgG concentration 0.5 mg/ml |
Applications | Immunohistology Frozen, Immunoprecipitation (IP), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti Human IRAK1 antibody recognizes human Interleukin-1 receptor-associated kinase 1 (IRAK1) an 80kD serine/threonine protein kinase designated IRAK containing a single protein kinase domain and a single death domain. IRAK is associated with IL-1 receptor subunits, and mediates a signalling cascade leading to NF-kB activation after IL-1 binding (Burns et al. 2000).Multiple isoforms of IRAK1 generated by alternative splicing have been described. Isoforms 1 and 2 are ubiquitously expressed (Jensen et al. 2001). Rabbit anti Human IRAK1 antibody recognizes isoform 1 but reactivity with other isoforms having partial deletions of the carboxy-terminal region has not been assessed. |
Immunogen | Buffer Solution: Phosphate buffered saline Antiserum Preparation: Antisera to human IRAK were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG prepared by ion exchange chromatography. Target Species: Human |
Other Names | [interleukin-1 receptor-associated kinase 1 isoform 2; Interleukin-1 receptor-associated kinase 1; interleukin-1 receptor-associated kinase 1; IRAK-1; Pelle homolog; interleukin-1 receptor-associated kinase 1], [IRAK1; IRAK1; IRAK; pelle; IRAK; IRAK-1] |
Gene, Accession # | [IRAK1], Gene ID: 3654, NCBI: NP_001020413.1, UniProt: P51617 |
Catalog # | MBS221583 |
Price | $375 |
Order / More Info | Human IRAK1 (C-TERMINAL) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |