Human IRAK1 (C-TERMINAL) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman IRAK1 (C-TERMINAL)
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesn/a
Isotypen/a
Formatunconjugated
Size0.1 mg
ConcentrationIgG concentration 0.5 mg/ml
ApplicationsImmunohistology Frozen, Immunoprecipitation (IP), Western Blot (WB)
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DescriptionRabbit anti Human IRAK1 antibody recognizes human Interleukin-1 receptor-associated kinase 1 (IRAK1) an 80kD serine/threonine protein kinase designated IRAK containing a single protein kinase domain and a single death domain. IRAK is associated with IL-1 receptor subunits, and mediates a signalling cascade leading to NF-kB activation after IL-1 binding (Burns et al. 2000).Multiple isoforms of IRAK1 generated by alternative splicing have been described. Isoforms 1 and 2 are ubiquitously expressed (Jensen et al. 2001). Rabbit anti Human IRAK1 antibody recognizes isoform 1 but reactivity with other isoforms having partial deletions of the carboxy-terminal region has not been assessed.
ImmunogenBuffer Solution: Phosphate buffered saline Antiserum Preparation: Antisera to human IRAK were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG prepared by ion exchange chromatography. Target Species: Human
Other Names[interleukin-1 receptor-associated kinase 1 isoform 2; Interleukin-1 receptor-associated kinase 1; interleukin-1 receptor-associated kinase 1; IRAK-1; Pelle homolog; interleukin-1 receptor-associated kinase 1], [IRAK1; IRAK1; IRAK; pelle; IRAK; IRAK-1]
Gene, Accession #[IRAK1], Gene ID: 3654, NCBI: NP_001020413.1, UniProt: P51617
Catalog #MBS221583
Price$375
Order / More InfoHuman IRAK1 (C-TERMINAL) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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