PLCgamma2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPLCgamma2
Clone[5H12-G10-C8]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2b
Formatunconjugated
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionEntrez Summary: The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4, 5-bisphosphate to 1D-myo-inositol 1, 4, 5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3. [provided by RefSeq, Mar 2014]. UniPort Summary Function: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1, 4, 5-trisphosph
ImmunogenImmunogen: Synthesized peptide of human PLCG2 (AA: phospho-Tyrosine 753 of human Phospholipase Cg2 (cERDINSLpYDVSRMYV)). Sequence Similarities: Contains 1 SH3 domain.
Other Names[FCAS3; APLAID; PLC-IV; PLC-gamma-2], [PLCG2; FCAS3; APLAID; PLC-IV; PLC-gamma-2]
Gene, Accession #[PLCgamma2], Gene ID: 5336, NCBI: NP_002652.2, UniProt: P16885
Catalog #MBS476791
Price$335
Order / More InfoPLCgamma2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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