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Antigenic Specificity | TXN |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity.ADF augments the expression of the interleukin-2 receptor TAC (IL2R/P55). |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence within amino acids 20 to the C-terminus of human TXN (NP 003320.2). |
Other Names | [TRX; TRDX; TRX1] |
Gene, Accession # | [TXN], Gene ID: 7295, NCBI: NP_001231867.1, UniProt: P10599 |
Catalog # | MBS8549617 |
Price | $280 |
Order / More Info | TXN Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |