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Antigenic Specificity | Mouse CD62L |
Clone | [Mel14] |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2a |
Format | unconjugated |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD62L is a 74-95 kD glycoprotein also known as L-selectin, LECAM-1, Ly-22, LAM-1, and MEL-14. It is a member of the selectin family and is expressed on the majority of B and naive T cells, a subset of memory T cells, monocytes, granulocytes, most thymocytes, and a subset of NK cells. CD62L is important in lymphocyte homing to high endothelial venules (HEV) in peripheral lymph nodes and leukocyte rolling on activated endothelium. CD62L also contributes to neutrophil emigration at inflammatory sites. CD62L is rapidly shed from lymphocytes and neutrophils upon cellular activation and the expression levels of CD62L (in conjunction with other markers) have been used to distinguish naive, effector, and memory T cells. CD62L has been reported to |
Immunogen | n/a |
Other Names | [Mouse CD62L; L-selectin; Sell; CD62 antigen-like family member L; LAM-1; LECAM1; Lymph node homing receptor; Ly-22; CD62L; Lnhr; Ly22] |
Gene, Accession # | [CD62L], Gene ID: 20343, NCBI: NP_035476.1, UniProt: P18337 |
Catalog # | MBS2553763 |
Price | $90, $110 |
Order / More Info | Mouse CD62L Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Barclay AN, et al. 1997. The Leukocyte Antigen FactsBook Academic Press. 2. Kishimoto TK, et al. 1990. P. Natl. Acad. Sci. USA 87:2244. 3. Tedder TF, et al. 1995. J. Exp. Med. 181:2259. |