TNF-alpha (Tumor Necrosis Factor alpha) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | TNF-alpha (Tumor Necrosis Factor alpha) |
| Clone | [4C6-H8] |
| Host Species | Mouse |
| Reactive Species | human, mouse, rat, rabbit, cat, dog, zebrafish |
| Isotype | IgM, kappa |
| Format | unconjugated |
| Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA at 1mg/ml) |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Tumor Necrosis Factor Alpha (TNF alpha) is a protein secreted by lipopolysaccharide-stimulated macrophages, and causes tumor necrosis when injected into tumor bearing mice. TNF alpha is believed to mediate pathogenic shock and tissue injury associated with endotoxemia. TNF alpha exists as a multimer of two, three, or five non-covalently linked units, but shows a single 17kDa band following SDS PAGE under non-reducing conditions. TNF alpha is closely related to the 25kDa protein Tumor Necrosis Factor beta (lymphotoxin), sharing the same receptors and cellular actions. TNF alpha causes cytolysis of certain transformed cells, being synergistic with interferon gamma in its cytotoxicity. Although it has little effect on many culture |
| Immunogen | Immunogen: A hexadecapeptide corresponding to aa115-130 (NGVELRDNQLVVPSEG) of human TNF-alpha, conjugated to thyroglobulin |
| Other Names | [APC1, Cachectin, Differentiation inducing factor (DIF), Macrophage cytotoxic factor (MCF), Necrosin, TNF alpha, TNF Macrophage Derived, TNF Monocyte Derived, TNF Superfamily Member 2, TNFA, TNFSF2, Tumor necrosis factor ligand superfamily member 2, Tumor Necrosis Factor Precursor], [TNF; TNF; DIF; TNFA; TNFSF2; TNLG1F; TNF-alpha; TNFA; TNFSF2; TNF-a; NTF; ICD1; ICD2] |
| Gene, Accession # | [TNF], Gene ID: 7124, NCBI: NP_000585.2, UniProt: P01375 |
| Catalog # | MBS438069 |
| Price | $190, $340, $340 |
| Order / More Info | TNF-alpha (Tumor Necrosis Factor alpha) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Bebok Z; Szekeres G; Horvath G; Duda E; Nemeth P. [Creation of monoclonal antibodies against tumor necrosis factor-alpha (TNF-alpha) and transforming growth factor alpha (TFG-alpha), their definition and possible use]. Orvosi Hetilap, 1993 Jun 13, 134(24):1303-7. Language: Hungarian |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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