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Antigenic Specificity | Mouse Mapk8 (Center), 239-268 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: rat, Xenopus) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This Mouse Mapk8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 239-268 amino acids from the Central region of mouse Mapk8. Mapk8 responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as JUN, JDP2 and ATF2 and thus regulates AP-1 transcriptional activity. In T-cells, JNK1 and JNK2 are required for polarized differentiation of T-helper cells into Th1 cells. Phosphorylates heat shock factor protein 4 (HSF4) (By similarity). |
Immunogen | n/a |
Other Names | [Mitogen-activated protein kinase 8; MAP kinase 8; MAPK 8; Stress-activated protein kinase JNK1; c-Jun N-terminal kinase 1; Mapk8; Jnk1; Prkm8] |
Gene, Accession # | [Mapk8], Gene ID: 26419, NCBI: NP_057909.1, UniProt: Q91Y86 |
Catalog # | MBS9208158 |
Price | $165, $370 |
Order / More Info | Mouse Mapk8 (Center), 239-268 Antibody from MYBIOSOURCE INC. |
Product Specific References | Sherrin, T., et al. J. Neurosci. 30(40):13348-13361(2010) Morel, C., et al. Mol. Cell. Biol. 30(19):4616-4625(2010) Gao, D., et al. J. Biol. Chem. 285(39):29965-29973(2010) Han, J.S., et al. Anticancer Res. 30(9):3407-3412(2010) Cellurale, C., et al. PLoS ONE 5 (8), E12469 (2010) : |