TIAF Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | TIAF |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mg |
| Concentration | 1 mg/mL |
| Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Two alternatively spliced transcript variants encoding different isoforms have been identified. TIAF Antibody: TIAF-1 (TGFB1-induced anti-apoptotic factor 1), also known as MYO18A, is a TGFB1-induced anti-apoptotic factor that functions to inhibit the cytotoxic effects of TNF-alpha, TRADD and FADD. It localizes to the nucleus and significantly up-regulated in activated helper T lymphocytes (TH2) in chronic kidney and liver allograft rejection. Suppression of TIAF1 expression by siRNA prevents UV irradiation-mediated p53 phosphorylation and nuclear translocation. TIAF1 is essential in the p53- and WOX1-mediated cell death and shows an aggregation-dependent control of tumor progression and metastasis, and regulation of cell death |
| Immunogen | Immunogen: TIAF antibody was raised against a 16 amino acid peptide near the amino terminus of human TIAF. Buffer: TIAF Antibody is supplied in PBS containing 0.02% sodium azide. |
| Other Names | [TIAF; MAJN; SPR210; TGFB1-induced apoptotic factor 1; 12 kDa TGF-beta-1-induced antiapoptotic factor; TGFB1-induced apoptotic factor 1], [TIAF1; TIAF1; MAJN; SPR210] |
| Gene, Accession # | [TIAF], Gene ID: 9220, NCBI: NP_004731, UniProt: O95411 |
| Catalog # | MBS153556 |
| Price | $375 |
| Order / More Info | TIAF Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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