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Antigenic Specificity | Mouse Fgr (Center) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | rat |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This Mouse Fgr antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 232-265 amino acids from the Central region of Mouse Fgr. Non-receptor tyrosine-protein kinase that transmits signals from cell surface receptors devoid of kinase activity and contributes to the regulation of immune responses, including neutrophil, monocyte, macrophage and mast cell functions, cytoskeleton remodeling in response to extracellular stimuli, phagocytosis, cell adhesion and migration. Promotes mast cell degranulation, release of inflammatory cytokines and IgE-mediated anaphylaxis. Acts downstream of receptors that bind the Fc region of immunoglobulins, such as MS4A2/FCER1B, FCER1G and FCGR2. Acts downstream of ITGB1 and I |
Immunogen | n/a |
Other Names | [Tyrosine-protein kinase Fgr; Proto-oncogene c-Fgr; p55-Fgr; Fgr] |
Gene, Accession # | [Fgr], Gene ID: 14191, NCBI: NP_034338.3, UniProt: P14234 |
Catalog # | MBS9205762 |
Price | $165, $370 |
Order / More Info | Mouse Fgr (Center) Antibody from MYBIOSOURCE INC. |
Product Specific References | Yi T.L.,et al.Oncogene 4:1081-1087(1989). King F.J.,et al.Oncogene 5:337-344(1990). Carninci P.,et al.Science 309:1559-1563(2005). Church D.M.,et al.PLoS Biol. 7:E1000112-E1000112(2009). Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases. |