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Antigenic Specificity | GRB10 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: At least three isoforms of GRB10 are known to exist; this antibody will detect all three isoforms. GRB10 Antibody: GRB10 belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules and function in diverse cellular processes. GRB10 is a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of GRB10 inhibits tyrosine kinase activity and results in growth suppression. GRB10 can also interact with the L isoform of the proapoptotic protein Bim. This gene is imprinted in a highly isoform- and tissue-specific manner, with expression observed from the paternal a |
Immunogen | Immunogen: GRB10 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human GRB10. Buffer: GRB10 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [GRB10; RSS; IRBP; MEG1; GRB-IR; Grb-10; GRBIR; KIAA0207; Growth factor receptor-bound protein 10; GRB10 adapter protein; growth factor receptor-bound protein 10], [GRB10; GRB10; RSS; IRBP; MEG1; GRB-IR; Grb-10; GRBIR; KIAA0207] |
Gene, Accession # | [GRB10], Gene ID: 2887, NCBI: NP_005302, UniProt: Q13322 |
Catalog # | MBS150671 |
Price | $375 |
Order / More Info | GRB10 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |