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Antigenic Specificity | TIMM8A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIMM8-TIMM13 complex mediates the import of proteins such as TIMM23, SLC25A12/ARALAR1 and SLC25A13/ARALAR2, while the predominant TIMM9-TIMM10 70 kDa complex mediates the import of much more proteins. Probably necessary for normal neurologic development. |
Immunogen | Immunogen: Recombinant human Mitochondrial import inner membrane translocase subunit Tim8 A protein (1-97AA) |
Other Names | [Mitochondrial import inner membrane translocase subunit Tim8 A; Deafness dystonia protein 1; X-linked deafness dystonia protein; TIMM8A; DDP; DDP1; TIM8A] |
Gene, Accession # | [TIMM8A], Gene ID: 1678, NCBI: NP_004076.1, UniProt: O60220 |
Catalog # | MBS7045636 |
Price | $120, $160 |
Order / More Info | TIMM8A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |