Edit |   |
---|---|
Antigenic Specificity | Human Serine/threonine-protein kinase 24 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | fluorescein (FITC) conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Serine/threonine-protein kinase that acts on both serine and threonine residues and promotes apoptosis in response to stress stimuli and caspase activation. Mediates oxidative-stress-induced cell death by modulating phosphorylation of JNK1-JNK2 (MAPK8 and MAPK9), p38 (MAPK11, MAPK12, MAPK13 and MAPK14) during oxidative stress. Plays a role in a staurosporine-induced caspase-independent apoptotic pathway by regulating the nuclear translocation of AIFM1 and ENDOG and the DNase activity associated with ENDOG. Phosphorylates STK38L on 'Thr-442' and stimulates its kinase activity. Regulates cellular migration with alteration of PTPN12 activity and PXN phosphorylation: phosphorylates PTPN12 and inhibits its activity and may regulate PXN phosphory |
Immunogen | Immunogen: Recombinant human Serine/threonine-protein kinase 24 protein Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-21400 |
Other Names | [Mammalian STE20-like protein kinase 3 Mammalian STE20-like protein kinase 3 N-terminal Mammalian STE20-like protein kinase 3 C-terminal STK24 MST3; STK3], [STK24; STK24; MST3; STK3; MST3B; STE20; HEL-S-95; MST3; STK3; MST-3; MST3/N; MST3/C] |
Gene, Accession # | Gene ID: 8428, NCBI: NP_001027467.2, UniProt: Q9Y6E0 |
Catalog # | MBS1488199 |
Price | $160, $235 |
Order / More Info | Human Serine/threonine-protein kinase 24 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |