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Antigenic Specificity | mGluR4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: mGluR4 antibody detects endogenous levels of total mGluR4. Description: mGluR4 metabotropic glutamate receptor 3, a G-protein coupled receptor for glutamate. L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity.Function: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.Subunit Structure: Interacts with PICK1.Simila |
Immunogen | Immunogen: A synthesized peptide derived from human mGluR4 Subcellular Location: Cell Membrane Tissue Specificity: Strongly expressed in the cerebellum. Expressed at low levels in hippocampus, hypothalamus and thalamus. No expression detected in liver. |
Other Names | [Glutamate receptor metabotropic 4; GPRC1D; Grm4; GRM4_HUMAN; Metabotropic glutamate receptor 4; mGlu4; mGluR4] |
Gene, Accession # | [mGluR4], Gene ID: 2914, NCBI: NP_000832.1, UniProt: Q14833 |
Catalog # | MBS9600106 |
Price | $240, $280 |
Order / More Info | mGluR4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |