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Antigenic Specificity | MAP4K2 (Center), 321-349 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: mouse) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This MAP4K2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 321-349 amino acids from the Central region of human MAP4K2. The protein encoded by this gene is a member of theserine/threonine protein kinase family. Although this kinase isfound in many tissues, its expression in lymphoid follicles isrestricted to the cells of germinal centre, where it mayparticipate in B-cell differentiation. This kinase can be activatedby TNF-alpha, and has been shown to specifically activate MAPkinases. This kinase is also found to interact with TNFreceptor-associated factor 2 (TRAF2), which is involved in theactivation of MAP3K1/MEKK1. |
Immunogen | n/a |
Other Names | [Mitogen-activated protein kinase kinase kinase kinase 2; B lymphocyte serine/threonine-protein kinase; Germinal center kinase; GC kinase; MAPK/ERK kinase kinase kinase 2; MEK kinase kinase 2; MEKKK 2; Rab8-interacting protein; MAP4K2; GCK; RAB8IP] |
Gene, Accession # | [MAP4K2], Gene ID: 5871, NCBI: NP_004570.2, UniProt: Q12851 |
Catalog # | MBS9208436 |
Price | $165, $370 |
Order / More Info | MAP4K2 (Center), 321-349 Antibody from MYBIOSOURCE INC. |
Product Specific References | Bailey, S.D., et al. Diabetes Care (2010) In press : Fidalgo, M., et al. J. Cell. Sci. 123 (PT 8), 1274-1284 (2010) : Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009) Wissing, J., et al. Mol. Cell Proteomics 6(3):537-547(2007) Chadee, D.N., et al. Mol. Cell. Biol. 22(3):737-749(2002) |