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Antigenic Specificity | RNF138 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total RNF138 protein. E3 ubiquitin-protein ligase. Together with NLK, involved in the ubiquitination and degradation of TCF/LEF. Also exhibits auto-ubiquitination activity in combination with UBE2K. May act as a negative regulator in the Wnt/beta-catenin-mediated signaling pathway.Wang L., Submitted (APR-2000) to the EMBL/GenBank/DDBJ databases.Ota T., Nat. Genet. 36:40-45(2004).Kalnine N., Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases. |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human RNF138. |
Other Names | [E3 ubiquitin-protein ligase RNF138; EC 6.3.2.-; RING finger protein 138; Nemo-like kinase-associated RING finger protein; NLK-associated RING finger protein] |
Gene, Accession # | [RNF138], Gene ID: 51444, NCBI: NP_001178253.2, UniProt: Q8WVD3 |
Catalog # | MBS9404729 |
Price | $200, $255 |
Order / More Info | RNF138 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |