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Antigenic Specificity | Stromal Interaction Molecule 1 (STIM1) |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG |
Format | unconjugated |
Size | 0.02 mL, 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunoprecipitation (IP), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a type 1 transmembrane protein that mediates Ca2+ influx after depletion of intracellular Ca2+ stores by gating of store-operated Ca2+ influx channels (SOCs). It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region, as well as early hematopoiesis, by mediating attachment to stromal cells. Mutations in this gene are associated with fatal classic Kaposi sarcoma, immunodeficiency due to defects in store-opera |
Immunogen | Source Note: This monoclonal antibody is produced by immunizing mice with a sythetic peptide(KLH coupled)corresponding to amino-terminal residues of human |
Other Names | [D11S4896E; GOK; stim1 {ECO:0000312|RGD:1306831}; Stromal interaction molecule 1; D11S4896E; GOK; IMD10; SIM; STIM1; STRMK; TAM; TAM1], [STIM1; STIM1; GOK; TAM; TAM1; IMD10; STRMK; D11S4896E;] |
Gene, Accession # | [STIM1], Gene ID: 6786, NCBI: NP_001264891.1, UniProt: Q13586 |
Catalog # | MBS435180 |
Price | $225, $350, $565 |
Order / More Info | Stromal Interaction Molecule 1 (STIM1) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |