Edit |   |
---|---|
Antigenic Specificity | LIR-1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: LIR-1 Polyclonal Antibody detects endogenous levels of LIR-1 protein. LILRB1 is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13. The leukocyte immunoglobulin like receptor B1 belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity |
Immunogen | Immunogen: Synthesized peptide derived from the N-terminal region of human LIR-1 |
Other Names | [Rabbit LIR-1; LILRB1; ILT2; LIR1; MIR7; Leukocyte immunoglobulin-like receptor subfamily B member 1; LIR-1; Leukocyte immunoglobulin-like receptor 1; CD85 antigen-like family member J; Immunoglobulin-like transcript 2; ILT-2; Monocyte/macrophage immunoglobulin-like rec] |
Gene, Accession # | [LIR-1], Gene ID: 10859, NCBI: NP_001075108.2, UniProt: Q8NHL6 |
Catalog # | MBS9703972 |
Price | $130, $220, $325 |
Order / More Info | LIR-1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |