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Antigenic Specificity | FBLN5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 3.1 mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total FBLN5 protein. The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis la |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthetic peptide corresponding to a region derived from internal residues of human fibulin 5 |
Other Names | [EVEC; UP50; ADCL2; ARMD3; DANCE; ARCL1A; FIBL-5] |
Gene, Accession # | [FBLN5], Gene ID: 10516, NCBI: NP_006320.2, UniProt: Q9UBX5 |
Catalog # | MBS9402890 |
Price | $255 |
Order / More Info | FBLN5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |