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Antigenic Specificity | JUN |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Western blot analysis of extracts of PC3 cells, using c-Jun antibody. Immunofluorescence analysis of A549 cell using Jun antibody. Blue: DAPI for nuclear staining. c-Jun is a member of the Jun Family containing c-Jun, JunB and JunD, and is a component of the transcription factor AP-1 (activator protein-1). AP-1 is composed of dimers of Fos, Jun and ATF family members and binds to and activates transcription at TRE/AP-1 elements (reviewed in 1). Extracellular signals including growth factors, chemokines and stress activate AP-1-dependent transcription. The transcriptional activity of c-Jun is regulated by phosphorylation at Ser63 and Ser73 through SAPK/JNK (reviewed in 2). Knock-out studies in mice have shown that c-Jun is essen |
Immunogen | Immunogen: Recombinant protein of human JUN |
Other Names | [JUN; Transcription factor AP-1; transcription factor AP-1; Jun proto-oncogene, AP-1 transcription factor subunit; Activator protein 1; AP1; Proto-oncogene c-Jun; V-jun avian sarcoma virus 17 oncogene homolog; p39], [JUN; JUN; AP1; AP-1; c-Jun; AP1] |
Gene, Accession # | [JUN], Gene ID: 3725, NCBI: AAA59197.1 |
Catalog # | MBS419405 |
Price | $385 |
Order / More Info | JUN Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |