CK-18 (Phospho) Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | CK-18 (Phospho) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | epitope affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | ELISA (EIA), Flow Cytometry (FC/FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody recognizes CK18 with a phosphorylated site of Ser33. It does not cross-react with non-phosphospecific peptide. Keratin polypeptides 8 (basic keratin) and 18 (acidic keratin) exist in combination as K8/K18 which are the cytoskeletal intermediate filament proteins of hepatocytes while K8/K18/K19 are the keratins of hepatobiliary ductal cells. Hepatocyte K8/K18 are highly abundant and behave as stress proteins with injury-inducible expression. K8 and K18 are cytoprotective stress proteins that play a central role in guarding hepatocytes from apoptosis. Hepatocellular carcinoma have been reportedly defined by the use of antibodies that recognize only cytokeratins 8 and 18. K18 Ser33 as an interphase phosphorylation site, which inc |
| Immunogen | n/a |
| Other Names | n/a |
| Gene, Accession # | [CK-18], Gene ID: 3875 |
| Catalog # | MBS460569 |
| Price | $285 |
| Order / More Info | CK-18 (Phospho) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Ku NO, Liao J, Omary MB, et al. Phosphorylation of human keratin 18 serine 33 regulates binding to 14-3-3 proteins. EMBO J. 1998 Apr 1; 17 (7):1892-906. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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