Edit |   |
---|---|
Antigenic Specificity | GLUR4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | AMPA(alphaamino3hydroxy5methyl4isoxazolepropionic acid), kainite, and NMDA(NmethylDaspartate) receptors are the three main families of ionotropic glutamategated ion channels. AMPA receptors (AMPARs) are comprised of four subunits (GluR 14), which assemble as homoor heterotetramers to mediate the majority of fast excitatory transmissions in the CNS. AMPARs are implicated in synapse formation, stabilization, and plasticity (1). AMPARs that lack GluR 2 are permeable to calcium, in contrast to GluR 2containing AMPARs (2). Posttranscriptional modifications (alternative splicing, nuclear RNA editing) and posttranslational modifications (glycosylation, phosphorylation) result in a very large number of permutations, finetuning the kinetic propertie |
Immunogen | Immunogen: A synthetic peptide of human GLUR4 |
Other Names | [GRIA4; GLUR4; GLURD; GluA4; GLUR4C], [GRIA4; GRIA4; GLUR4; GLURD; GluA4; GLUR4C; GLUR4; GluR-4; GluR4; GluA4] |
Gene, Accession # | Gene ID: 2893, NCBI: NP_000820.3, UniProt: P48058 |
Catalog # | MBS127641 |
Price | $200, $275, $430 |
Order / More Info | GLUR4 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Palmer, C.L. et al. (2005) Pharmacol Rev 57, 25377. 2. CullCandy, S. et al. (2006) Curr Opin Neurobiol 16, 28897. 3. Gomes, A.R. et al. (2007) Traffic 8, 259269. |