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Antigenic Specificity | TBC1D3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: TBC1D3 antibody detects endogenous levels of total TBC1D3. Function: Acts as a GTPase activating protein for RAB5. Does not act on RAB4 or RAB11.Post-translational Modifications: Ubiquitinated by a CUL7-based E3 ligase, which leads to proteasomal degradation. Palmitoylation is required for membrane localization and protects TBC1D3 from ubiquitination. |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Plasma Membrane Tissue Specificity: Expressed in liver, skeletal muscle, kidney, pancreas, spleen, testis, ovary, small intestine and peripheral blood leukocytes. Overexpressed in prostate cancers. |
Other Names | [PRC17; TBC1 domain family member 3; TBC1 domain family member 3F; TBC1D3; TBC1D3F; TBC3F_HUMAN; TRE17 alpha protein; TRE17] |
Gene, Accession # | [TBC1D3], Gene ID: 414060, NCBI: NP_001001418.5, UniProt: Q8IZP1 |
Catalog # | MBS9604807 |
Price | $240, $280 |
Order / More Info | TBC1D3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |