DLG1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityDLG1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionSpecificity: DLG1 antibody detects endogenous levels of total DLG1. Function: Essential multidomain scaffolding protein required for normal development (By similarity). Recruits channels, receptors and signaling molecules to discrete plasma membrane domains in polarized cells. May play a role in adherens junction assembly, signal transduction, cell proliferation, synaptogenesis and lymphocyte activation. Regulates the excitability of cardiac myocytes by modulating the functional expression of Kv4 channels. Functional regulator of Kv1.5 channel.Subunit Structure: Homotetramer (Probable). Interacts (via guanylate kinase-like domain) with DLGAP1, DLGAP2, DLGAP3, DLGAP4 and MAP1A (By similarity). Interacts (via guanylate kinase-like domain)
ImmunogenImmunogen: A synthesized peptide derived from human DLG1 Subcellular Location: Membrane. Basolateral Cell Membrane. Endoplasmic Reticulum Membrane. Cell Junction, Synapse, Postsynaptic Cell Membrane, Postsynaptic Density. Cell Junction, Synapse. Cell Membrane, Sarcolemma. Colocalizes with EPB41 at regions of intercellular contacts. Basolateral in epithelial cells. May also associate with endoplasmic reticulum membranes. Mainly found in neurons soma, moderately found at postsynaptic densities (By
Other Names[Discs large homolog 1; discs large, Drosophila, homolog of, 1; discs, large homolog 1 (Drosophila); Disks large homolog 1; dJ1061C18.1.1; DKFZp761P0818; DKFZp781B0426; DLG 1; DLG1; DLG1_HUMAN; DLGH 1; DLGH1; hDlg; Presynaptic protein SAP97; SAP 97; SAP-97; SAP97; Synapse associated protein 97; Synapse-associated protein 97]
Gene, Accession #[DLG1], Gene ID: 1739, NCBI: NP_001091894.1, UniProt: Q12959
Catalog #MBS9608806
Price$240, $280
Order / More InfoDLG1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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