Human B7-H4 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Human B7-H4 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Human B7-H4 |
| Clone | [MIH43] |
| Host Species | Mouse |
| Reactive Species | n/a |
| Isotype | IgG1 |
| Format | unconjugated |
| Size | 0.2 mg |
| Concentration | IgG concentration 1.0 mg/ml |
| Applications | Immunohistology Frozen, Flow cytometry (FC/FACS), Immunohistology Paraffin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Mouse anti Human B7-H4 antibody, clone MIH43 recognizes human B7-H4, also known as B7x, a costimulatory protein which is reported to function as a negative regulator of T-cell mediated immunity. Although B7-H4 binds an unknown receptor, it is thought to deliver an inhibitory signal to T-cells preventing their proliferation, cell cycle progression and interleukin-2 production. B7-H4 deficient mice are only minimally affected; suggesting B7-H4 is important in the fine tuning of the T-cell mediated immune response. B7-H4 is expressed on activated T-cells, B-cells, monocytes and dendritic cells. Aberrant expression has been associated with cancers of the lung, breast and ovary in humans. B7-H4 could be a useful prognostic marker in Renal Cell C |
| Immunogen | Immunogen: Human B7-H4 Histology Positive Control Tissue: Tonsil, breast carcinoma Buffer Solution: Phosphate buffered saline Target Species: Human |
| Other Names | [V-set domain-containing T-cell activation inhibitor 1 isoform 2; V-set domain-containing T-cell activation inhibitor 1; V-set domain-containing T-cell activation inhibitor 1; B7 family member, H4; B7 homolog 4; B7 superfamily member 1; T cell costimulatory molecule B7x; T-cell costimulatory molecule B7x; VTCN1; immune costimulatory protein B7-H4; V-set domain containing T cell activation inhibitor 1; B7 homolog 4; B7-H4; B7h.5; Immune costimulatory protein B7-H4; Protein B7S1; T-cell costimulatory molecule B7x], [VTCN1; VTCN1; B7X; B7H4; B7S1; B7-H4; B7h.5; VCTN1; PRO1291; B7-H4] |
| Gene, Accession # | [B7-H4], Gene ID: 79679, NCBI: NP_001240778.1, UniProt: Q7Z7D3 |
| Catalog # | MBS214416 |
| Price | $430 |
| Order / More Info | Human B7-H4 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies