Mre11 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Mre11 |
| Clone | monoclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.03 mg, 0.1 mg, 0.1 mg |
| Concentration | n/a |
| Applications | Immunohistochemistry (IHC), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA Recombinantion, maintenance of telomere integrity and meiosis. The complex possesses single-strand endonuclease activity and double-strand- specific 3'-5' exonuclease activity, which are provided by MRE11A. RAD50 may be required to bind DNA ends and hold them in close proximity. This could facilitate searches for short or long regions of sequence homology in the recombining DNA templates, and may also stimulate the activity of DNA ligases and/or restrict the nuclease activity of MRE11A to prevent nucleolytic degradation past a given point (PubMed: 9651580, PubMed: 9590181, PubMed: 9705271, PubMed: 11741547). The complex may also be required for |
| Immunogen | Immunogen: A synthesized peptide derived from human Mre11. Subcellular Localization: Nucleus. Chromosome, telomere. Localizes to discrete nuclear foci after treatment with genotoxic agents. |
| Other Names | [Double-strand break repair protein MRE11A; Meiotic Recombinantion 11 homolog 1; MRE11 homolog 1; Meiotic Recombinantion 11 homolog A; MRE11 homolog A; MRE11A; HNGS1; MRE11], [MRE11A] |
| Gene, Accession # | [Mre11], Gene ID: 4361, NCBI: NP_005581.2, UniProt: P49959 |
| Catalog # | MBS179431 |
| Price | $160, $340, $340 |
| Order / More Info | Mre11 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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